In March 2022, the United Nations opened international negotiations to put an end to plastic pollution. In 2023, the Sorbonne University Alliance mobilized to contribute to this scientific and political effort. It has brought together researchers from Sorbonne University and the National Museum for Natural History. It is the first French university accredited by UNEP to take part in international negotiations. In this collection, some forty researchers have written twenty fact sheets, driven by a concern for pedagogy and the imperative of rigor. Pedagogy, with a succinct form, free of technical vocabulary. Scientific rigor, with references at the bottom of each page to the best and most recent publications on each of the subjects covered. The authors are chemists, agronomists, microbiologists, virologists, ecotoxicologists, neuroendocrinologists, ecologists, oceanographers, marine biologists... Only such a wide range of skills makes it possible to approach a crisis of universal dimensions such as plastic pollution.