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https://doi.org/10.23919/eumc....
Article . 2019 . Peer-reviewed
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Design and Implementation of Injection Locked Oscillator Biosensors

Authors: Babay, M.; Dalmay, C.; Barelaud, B.; Durmaz, E.C.; Kaynak, C. Baristiran; Kaynak, M.; Cordeau, D.; +1 Authors

Design and Implementation of Injection Locked Oscillator Biosensors

Abstract

This paper presents the design and the implementation of a Lab-on-Chip biosensor, based on injection locked oscillators (ILO) integrated on a BiCMOS SiGe technology, dedicated to the analysis of biological cells by dielectric spectroscopy at microwave frequencies. The proposed circuit is able to evaluate the dielectric response of suspended cells circulating in a microfluidic channel. Under these conditions, a sensing accuracy of a few attoF is necessary to discriminate differences between cells, which in the case of oscillators in free running frequency would require to be able to generate variations of the oscillation frequency of the order of 10 kHz in the vicinity of 5 GHz. With the proposed biosensor, post layout simulations show that it should be possible to measure effects of 10 attoF capacitive variation. Hence, the architecture of injection locked oscillators may prove to be the much more relevant approach at the price of a total current consumption of 37 mA from a 2.5 V supply voltage.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average