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γ‐Aminobutyric acid transaminase deficiency impairs central carbon metabolism and leads to cell wall defects during salt stress in Arabidopsis roots

Authors: Renault, Hughes; El Amrani, Abdelhak; Berger, Adeline; Mouille, Gregory; Soubigou-Taconnat, Ludivine; Bouchereau, Alain; Deleu, Carole;

γ‐Aminobutyric acid transaminase deficiency impairs central carbon metabolism and leads to cell wall defects during salt stress in Arabidopsis roots

Abstract

GABA (γ‐aminobutyric acid) is a ubiquitous non‐protein amino acid that commonly accumulates in plants in response to stressful conditions. However, functions of GABA in plants remain still unclear. In this study, we provide metabolic and transcriptional evidences that GABA metabolism is involved in central carbon metabolism regulation upon salt stress in roots. Furthermore, we show that GABA transaminase deficiency results in deleterious consequences for root development and cell wall elaboration during salt stress. Our work thus highlights the critical function of GABA metabolism in root metabolic acclimation to saline conditions.

Keywords

570, Arabidopsis thaliana, Transcription, Genetic, polyamines, TCA cycle., Arabidopsis, Succinic Acid, Glutamic Acid, glutamate, Sodium Chloride, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Plant Roots, Gene Expression Regulation, Enzymologic, GABA, Cell Wall, Gene Expression Regulation, Plant, Stress, Physiological, Polyamines, TCA cycle, Transaminases, salt tolerance, Comparative Genomic Hybridization, Arabidopsis Proteins, succinate, Carbon, Hypocotyl, [SDE.BE] Environmental Sciences/Biodiversity and Ecology, sugars, [SDE.BE]Environmental Sciences/Biodiversity and Ecology

  • BIP!
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    123
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
123
Top 1%
Top 10%
Top 10%
bronze