Abstract We studied the site ecology of Salvia brachyodon (Lamiaceae), a narrow endemic of the eastern Adriatic, which is now restricted to only three sites, using the sigmatistic method and numerical analyses. Four floristically and ecologically well-defined groups of stands, representing different syntaxa, were identified, corresponding to the sampling sites. The majority of stands represent dry eastern (sub)Mediterranean rocky grasslands at different successional stages towards (sub)Mediterranean forest vegetation. Compared to the evolutionary and ecologically closely related and sympatric S. officinalis, the morphologically easily distinguishable S. brachyodon differs in its flowering phenology and prefers relatively cooler, wetter, deeper and nutrient richer soils, which are developed on dolomite or dolomitic limestone at higher elevated sites. Despite its ability to cope with interspecific competition by means of clonal reproduction better than its congener, the populations are severely threatened by abandonment of traditional land use and by fires, making the species endangered (EN) according to IUCN criteria.