The aim of this paper is to give generating functions for parametrically generalized polynomials that are related to the combinatorial numbers, the Bernoulli polynomials and numbers, the Euler polynomials and numbers, the cosine-Bernoulli polynomials, the sine-Bernoulli polynomials, the cosine-Euler polynomials, and the sine-Euler polynomials. We investigate some properties of these generating functions. By applying Euler’s formula to these generating functions, we derive many new and interesting formulas and relations related to these special polynomials and numbers mentioned as above. Some special cases of the results obtained in this article are examined. With this special case, detailed comments and comparisons with previously available results are also provided. Furthermore, we come up with open questions about interpolation functions for these polynomials. The main results of this paper highlight the existing symmetry between numbers and polynomials in a more general framework. These include Bernouilli, Euler, and Catalan polynomials.