We discuss the observed deviations in $b \to s \ell^+ \ell^-$ processes from the Standard Model predictions and present global fits for both hadronic effects and the New Physics description of these anomalies. We investigate whether the different anomalies can be described by a consistent New Physics effect. We consider all the possible relevant new physics contributions to the semileptonic $b \to s$ transitions. Moreover, we study the prospects of future LHCb upgrade for establishing New Physics with the theoretically clean observables.