India is one of the highest Mango producing countries in the world which accounts for 62% of the total world production of Mango. It is estimated that mango consists of edible pulp 33-85%, kernel-9-40%, and inedible peel-7-24%. Due to this during industrial Mango processing, a large quantity of waste is generated which has serious disposable problems. One of the solutions is to use this waste as feed for animals due to this there will be less completion for the ingredients which are used for human consumption. But the Mango seed kernel which is a waste from processing can be used as a feed ingredient in fish feed. But the problem is using this product in feed is that it contains anti-nutrients and toxic components such as saponins, lectins, tannins, trypsin inhibitors, and cyanogenic glycosides which make them unsafe as protein and carbohydrate sources in livestock production. Many simple processes are been reported for reduction or removal of ant nutritional factor and toxic components are boiling, drying, soaking, leaching and fermentation. If mango seed kernel waste is managed properly it will be an additional asset to the mango processor, fish farmers and fish feed mill owners, etc. without compromising the environment.