The study was designed to assess and evaluate reading comprehension of secondary school students of Karachi in both government and private sector. Reading tests were conducted for 100 boys and 100 girls at secondary level and their score were compared to find out differences and correlation. Two questionnaires were also designed to find out practices and problems of reading comprehension. The data was analyzed and results revealed that there is a marked difference between the scores of students and practices of teachers for teaching of reading. Based on findings suitable recommendations were made.