This study thoroughly examines Health, Safety and Environmental (HSE) practices in the Liquefied Natural Gas (LNG) industry, a sector pivotal to the global energy landscape. The paper delves into the complexities and evolving nature of HSE practices, underscoring the industry's critical role in energy transition and its impact on environmental sustainability. The aim is to synthesize current challenges, assess risk management strategies, evaluate regulatory compliance and explore the influence of technological advancements and human factors on HSE practices. Through a systematic review and meta-analysis approach, the study meticulously analyzes peer-reviewed literature, focusing on the LNG industry's HSE practices since the year 2000. This comprehensive methodological framework ensures an unbiased synthesis of existing research, providing insights into trends, gaps and future research directions. Key findings reveal significant HSE challenges, including operational risks, environmental impacts and safety concerns. The study highlights the efficacy of current risk management strategies, emphasizing the need for comprehensive methodological approaches. It also sheds light on the multifaceted nature of regulatory compliance within the industry, stressing the importance of a compliance-oriented organizational culture and technological adaptation. The study concludes with recommendations for continuous improvement in HSE practices, leveraging technological innovations, fostering a compliance-oriented culture and adopting a multifaceted approach to manage complex HSE challenges. It advocates for balancing economic growth with environmental responsibility and safety, ensuring the LNG industry's sustainable development. This paper contributes significantly to the body of knowledge on HSE practices in the LNG industry and serves as a foundation for future research and policy development in this critical energy sector.