The aim of this study was the relationship betweengoal setting, Self-efficacy, Self-esteem withacademic achievementof high school girls. The study included all students in the third year of Khorramshahr, were enrolled in the academic year 2014-2015.The research sample consisted of 200 students that selected by multistage sampling. Instrument consisted of goal orientation questionnaire, general self-efficacy scale, Coppersmith self-esteem scale and Herman's achievement motivation questionnaire. The Results showed that. Simple correlation coefficients are significant at the α=0.05, showed that between goal setting and goal setting to goal, skill and attitude, self-esteem and self-efficacy and its components and its components There is a significant relationship with a female student academic achievement and the avoidance goals and academic achievement of female students is not significant positive relationship. The results of stepwise regression analysis have shown that prediction of the motivation of female students' academic achievement on the target components (for the purpose of mastery, approach and avoidance), self-efficacy (desire to initiate behavior, desire to continue trying to complete behavior and resistance to obstacles) and self-esteem (self-esteem, social, family, and educational). Keywords: goal setting, self-efficacy, self-esteem, academic achievement.