Polypodiaceae is notable for being one of the richest, most diverse, and abundant groups of ferns in tropical and subtropical forests. Currently, 65 genera and approximately 1652 species are recognized in the family. Pleopeltis is a monophyletic genus and comprises approximately 90 species, most of which are exclusive to the Neotropics. The aim of this scientific contribution is a taxonomic treatment of the Pleopeltis species occurring in Brazil. It has been based on the morphological data of specimens from Brazilian and foreign herbaria, as well as on observations and collections made in the field. Eighteen species are recognized in Brazil and occur in all Brazilian biomes, notably the Atlantic Forest (16 spp.). At least one species occurs in all Brazilian states, and the states of Espírito Santo and Minas Gerais (southeastern Brazil) are the richest (11 spp. each). According to the Brazilian Flora Red List, three species are officially threatened, P. alborufula and P. monoides are endangered, and P. trindadensis is critically endangered; however, we suggest including two more species in the official list: P. aturensis and P. stolzei. The taxonomic treatment includes a genus description, identification key to the species, synonyms, species description, distribution maps, illustrations, list of specimens studied, taxonomic comments, and information on habitat and distribution.