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Fluorinated carbohydrates as chemical probes for molecular recognition studies. Current status and perspectives

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2020 Belgium, France, Spain English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Society Reviews, volume 49, pages 3,863-3,888 (issn: 0306-0012, eissn: 1460-4744, Copyright policy )Funded by:UKRI | Investigating lipophilici..., EC | RECGLYCANMR
Authors: Linclau, Bruno; Ardá, Ana; Reichardt, Niels-Christian; Sollogoub, Matthieu; Unione, Luca; Vincent, Stéphane; Jiménez-Barbero, Jesús;

doi: 10.1039/c9cs00099b

pmid: 32520059

handle: 10810/46950

Fluorinated carbohydrates as chemical probes for molecular recognition studies. Current status and perspectives

Abstract

Fluorinated carbohydrates have become indispensable in glycosciences. This contribution provides an overview of how fluorine introduction modifies physical and chemical properties of carbohydrates along with selected examples of its applications.

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Keywords

Halogenation, Carbohydrates, NMR, FLUORINE, GLYCOMIMETICS, MOLECULAR RECOGNITION, aromatic interactions, udp-galactopyranose mutase, conformational behavior, Neoplasms, [CHIM] Chemical Sciences, Animals, Humans, enantioselective synthesis, Glycosides, Enzyme Inhibitors, hydrogen-bond acidity, Vaccines, Synthetic, mechanism-based inhibitors, metabolic-inhibitors, chemoenzymatic synthesis, nuclear-magnetic-resonance, Molecular Probes, Positron-Emission Tomography, organic fluorine

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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