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Volumetric parcellation of the cardiac right ventricle for regional geometric and functional assessment

Authors: Gabriel Bernardino; Amir Hodzic; Hélène Langet; Damien Legallois; Mathieu De Craene; Miguel Ángel González Ballester; Eric Saloux; +1 Authors

Volumetric parcellation of the cardiac right ventricle for regional geometric and functional assessment

Abstract

3D echocardiography is an increasingly popular tool for assessing cardiac remodelling in the right ventricle (RV). It allows quantification of the cardiac chambers without any geometric assumptions, which is the main weakness of 2D echocardiography. However, regional quantification of geometry and function is limited by the lower spatial and temporal resolution and the scarcity of identifiable anatomical landmarks. We developed a technique for regionally assessing the 3 relevant RV regions: apical, inlet and outflow. The method's inputs are end-diastolic (ED) and end-systolic (ES) segmented 3D surface models. The method first defines a partition of the ED endocardium using the geodesic distances from each surface point to apex, tricuspid valve and pulmonary valve: the landmarks that define the 3 regions. The ED surface mesh is then tetrahedralised, and the endocardial-defined partition is interpolated in the blood cavity via the Laplace equation. For obtaining an ES partition, the endocardial partition is transported from ED to ES using a commercial image-based tracking, and then interpolated towards the endocardium, similarly to ED, for computing volumes and ejection fraction (EF). We present a full assessment of the method's validity and reproducibility. First, we assess reproducibility under segmentation variability, obtaining intra- and inter- observer errors (4-10% and 10-23% resp.). Finally, we use a synthetic remodelling dataset to identify the situations in which our method is able to correctly determine the region that has remodelled. This dataset is generated by a novel mesh reconstruction method that deforms a reference mesh, locally imposing a given strain, expressed in anatomical coordinates. We show that the parcellation method is adequate for capturing local circumferential and global circumferential and longitudinal RV remodelling.

Countries
Spain, Belgium, France
Keywords

FOS: Computer and information sciences, Technology, [SDV]Life Sciences [q-bio], Heart Ventricles, Ventricular Dysfunction, Right, Computer Vision and Pattern Recognition (cs.CV), Anatomical parcellation, geometry processing, Computer Science - Computer Vision and Pattern Recognition, Echocardiography, Three-Dimensional, 610, Computer Science, Artificial Intelligence, DISEASE, 09 Engineering, anatomical parcellation, Engineering, Cardiac remodelling, FOS: Electrical engineering, electronic engineering, information engineering, Humans, Engineering, Biomedical, 11 Medical and Health Sciences, 40 Engineering, Science & Technology, Radiology, Nuclear Medicine & Medical Imaging, Image and Video Processing (eess.IV), cardiac remodelling, Reproducibility of Results, 32 Biomedical and clinical sciences, Geometry processing, Electrical Engineering and Systems Science - Image and Video Processing, [SDV] Life Sciences [q-bio], Nuclear Medicine & Medical Imaging, Echocardiography, Computer Science, Ventricular Function, Right, Computer Science, Interdisciplinary Applications, Life Sciences & Biomedicine

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    popularity
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    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Top 10%
Average
Top 10%
Green
hybrid