The article shows the economically valuable features the spring barley and analyzes the most relevant varieties for growing on the farm. It is studied that many varieties of the spring barley with competitive genetic potential of productivity have been created in Ukraine, which in 2021 makes 181 varieties. It is shown that the use the best varieties and high quality seeds is one the most effective means of economic growth in the agro-industrial sector. In recent years, there has been an increase in the spread various diseases of plants spring barley, leading to significant yield losses. We analyzed modern methods of plant selection which allows faster searching new markers with partial resistance to diseases. It is shown that one the strategic direction of modern agriculture development is its biologization — the use of biological means to obtain quality products crop and the reproduction of fertility soils. Modern views on the effective use of biological preparations of different spectrum of action in the technologies of growing crops were presented. It is established that the use ecologycally safe technologies for growing spring barley is relevant. This does not only increase resistance to adverse conditions and phytopathogens, but increases yields and improves grain quality. We analyzed liquid microfertilizer Oracle and complex natural-synthetic preparation Vimpel 2, products of Dolyna company. These preparations have an inhibitory effect on plant diseases and building stimuli of natural plant immunity. Analysis of scientific and technical literature allows us to conclude that the urgent task is to find ways to regulate phytopathogenic microorganisms to ensure the harmonious flow of biological processes in the soil, improve plant nutrition, and the formation of full-fledged plant-microbial associations, which allows controlling the development and spread of pathogens.