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Veterinary Immunology and Immunopathology
Article . 1994 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
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Analyses of mAb reactive with porcine CD8

Authors: Saalmüller, A.; Aasted, B.; Canals, A.; Dominguez, J.; Goldman, T.; Lunney, J. K.; Maurer, S.; +7 Authors

Analyses of mAb reactive with porcine CD8

Abstract

Among all mAb submitted to the first porcine CD workshop, based on FCM analyses six mAb could be identified to recognize the porcine CD8 analogue (workshop Nos. 004, 051, 052, 053, 108 and 109). In immunoprecipitation studies three mAb (Nos. 004, 108 and 109) recognized an antigen with an apparent molecular mass of about 35 kDa under reducing conditions and about 70 kDa under non-reducing conditions. The molecular masses of the antigens recognized by the three other mAb (Nos. 051, 052 and 053) are still unknown. Epitope analyses performed by blocking experiments led to the determination of two CD8 epitopes: CD8a and CD8b. CD8a is recognized by mAb Nos. 004, 051 and 052, and CD8b by Nos. 053, 108 and 109.

Keywords

Swine, CD8 Antigens, T-Lymphocytes, Antibodies, Monoclonal, Flow Cytometry, Molecular Weight, Epitopes, Antibody Specificity, Animals

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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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