Growing of highly productive perennial plants becomes the guarantee of opportunity of stable provision with raw materials for the production of solid biofuels in modern conditions. The purpose of the research was to increase yielding capacity of Miscanthus biomass at the expense of the nutritional background and foliar top dressing. Four-year observations of the condition of Miscanthus plantations were performed at Station in the Forest-steppe zone of Ukraine during 2016‒2019. Over the years of observations, a noticeable effect of background nutrition in combination with foliar feeding, plant growth regulators and growth stimulants and their one-time and double treatments has been revealed. The highest result was obtained in 2016 with an excessive amount of moisture during the growing season ‒ 392 mm. In the first variant of factor A with the one-time treatment by means of preparation Quantum Gold the leaf surface was 46.7 thousand m2/ha; on the nutritional background N30P30K30 with one-time treatment by means of preparation Vympel-K ‒ 45.6 thousand m2/ha; with increase of the dose of mineral fertilizers on the nutritional background twice (N60P60K60) at one-time treatment with the preparation Vympel-K the leaf surface was 45 thousand m2/ha. The lowest results were obtained in 2017, when 183 mm of precipitation was registered during the entire growing season. In the first variant of the same factor A at one-time treatment with the preparation Quantum Gold the leaf surface was 3.8 thousand m2/ha, in the second variant, when treated with the preparation Vympel-K, its leaf surface was 7.4 thousand m2/ha, in the third variant (control) ‒ 11.4 thousand m2/ha. In the control variants of factor B, the leaf surface area with the application of mineral fertilizers (second and third variants of factor A) increased. In consideration of the data obtained, it can be argued that the application of mineral fertilizers had the positive effect on plant growth and development, even with a critically minimal amount of precipitations. The application of the preparation Quantum Gold significantly affects the growth and development of the aboveground part of the Miscanthus gigantic. The application of the preparation Vympel-K stimulates the development of the root system and increases the yielding capacity of the investigated crop