In the era of big data and fast changing markets, timely information and knowledge for making business decisions make a competitive advantage. Rapid changes cause disruption of organizations, especially new information technologies and organizations that are born digital. To cope, many organizations undergo digital transformation and change their business models. In such conditions knowledge management is more important than ever, but the question is whether companies recognize its large potentials, from supporting digital business and digital workforce to preserving and delivering critical knowledge at any time. In this paper we discuss benefits that knowledge management can give organizations in disruptive times together with issues and challenges that arise. Also, an overview of new information technologies that may be incorporated into knowledge management systems and contribute to those benefits is presented, such as technologies connected to artificial intelligence. This leads to examination how disruptive times and technologies change knowledge management itself and whether and how they affect processes of creating, managing, sharing and using organizational knowledge.