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Guidance on allergenicity assessment of genetically modified plants

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2017Embargo end date: 27 Jan 2018 Italy, United Kingdom, Spain, Switzerland, France Publisher:WileyJournal:EFSA Journal, volume 15 (issn: 1831-4732, eissn: 1831-4732, Copyright policy )
Authors: EFSA Panel on Genetically Modified Organisms (GMO); Naegeli, Hanspeter; Birch, Andrew Nicholas; Casacuberta, Josep; Schrijver, Adinda de; Gralak, Mikolaj Antoni; Guerche, Philippe; +21 Authors

doi: 10.2903/j.efsa.2017.4862 , 10.5167/uzh-144684

pmid: 32728397

pmc: PMC7384481

handle: 10261/194130 , 11577/3243051

Guidance on allergenicity assessment of genetically modified plants

Abstract

This document provides supplementary guidance on specific topics for the allergenicity risk assessment of genetically modified plants. In particular, it supplements general recommendations outlined in previous EFSA GMO Panel guidelines and Implementing Regulation (EU) No 503/2013. The topics addressed are non-IgE-mediated adverse immune reactions to foods, in vitro protein digestibility tests and endogenous allergenicity. New scientific and regulatory developments regarding these three topics are described in this document. Considerations on the practical implementation of those developments in the risk assessment of genetically modified plants are discussed and recommended, where appropriate. (C) 2017 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

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Keywords

allergenicity assessment, GMO, Nutrition. Foods and food supply, [SDV]Life Sciences [q-bio], Chemical technology, newly expressed proteins, 10079 Institute of Veterinary Pharmacology and Toxicology, TP1-1185, Industrial biotechnology, endogenous allergenicity, 630, [SDV] Life Sciences [q-bio], Scientific Opinion, 570 Life sciences; biology, TX341-641, guidance, Biotechnology

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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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