A significant portion of harvested produce never reaches the consumer due to, postharvest diseases. Various chemicals have been used to reduce the incidence of postharvest diseases. Many of these materials have been removed from the market in recent years due to economic, environmental, or health concerns. Although somewhat limited in the range of diseases controlled, chlorination is effective when combined with proper postharvest handling practices. Additionally, it is a relatively inexpensive postharvest disease control method that poses little threat to health or the environment. The proper use of chlorination in the management of postharvest diseases in fresh fruits and vegetables is discussed.