Abstract In terms of semiotics, all human cultural phenomena and intellectual activities are expressed by signs to present different human achievements and the significance of human existence; they are all symbolized activities. The linguistic cultural study has a long history and is well achieved, but for the in-depth research there are more fields to cultivate. The study of linguistic culturology in terms of semiotics could result in some productive attempts: the study of the text of signs providing the research basis, the focus lying in the variations of signs information, and the secondary modeling system of signs making the research sphere; the dialogic relationship of signs building up the structure, and the dynamic equilibrium of semiosphere constructing the measurement. Above all, in terms of semiotics, the study of linguistic culturology must lead to new developments and discoveries.