Scalable quantum photonics relies on interfacing many optical components under mutually compatible operating conditions. To that end, we demonstrate that spontaneous parametric down-conversion (SPDC) in nonlinear waveguides, a standard technology for generating entangled photon pairs, squeezed states, and heralded single photons, is fully compatible with cryogenic operating conditions required for superconducting detectors. This is necessary for the proliferation of integrated quantum photonics in integration platforms exploiting quasi-phase-matched second-order nonlinear interactions. We investigate how cryogenic operation at 4 K affects the SPDC process by comparing the heralding efficiency, second-order correlation function, and spectral properties with operation at room temperature.