This book provides an introduction to nanofluidics in a simple manner and can be easily followed by senior undergraduate students, graduate students, and other researchers who have some background in fluid mechanics. The book covers the main topics about the fundamentals of nanofluidics and how it differs from classic fluid mechanics. It also describes the methodologies of nanofluidics, including numerical approaches, e.g., molecular dynamics simulation and experimental techniques. Fundamental physics and new phenomena in nanofluidics are the major concerns of this book.