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Neurophysiologic Assessment of Endolymphatic Hydrops

descriptionPublicationkeyboard_double_arrow_right Article 01 May 1983 English Publisher:SAGE PublicationsJournal:Annals of Otology, Rhinology & Laryngology, volume 93, pages 225-228 (issn: 0003-4894, eissn: 1943-572X,

Authors: Michael A. Sikora; Tetsuo Morizono;

doi: 10.1177/000348948409300307 , 10.1121/1.2020573

pmid: 6732107

Neurophysiologic Assessment of Endolymphatic Hydrops

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Abstract

An electrophysiological method for assessing endolymphatic hydrops of the cochlea in an animal model of Meniere's disease is described. Eighth nerve gross action potentials (AP) were evoked by tone bursts presented at discrete phases of a simultaneously delivered 50-Hz pure tone. Hydropic cochleas showed significantly less modulation of AP amplitude and latency than normal cochleas. This method may be useful in objectively evaluating Meniere's disease with electrocochleography.

Related Organizations

University of Minnesota Morris
United States

Keywords

Guinea Pigs, Auditory Threshold, Basilar Membrane, Electrophysiology, Disease Models, Animal, Cochlear Microphonic Potentials, Evoked Potentials, Auditory, Reaction Time, Animals, Meniere Disease

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