This paper introduces the up-dated taxonomic placement of 106 genera of Hepaticae and 233 genera of Musci known from Venezuela. Besides, a summarized version from the geographical distribution in Venezuela of 383 species of Hepaticae and 1009 species of mosses is presented. Information was derived from an exhaustive revision of bryophyte collections in the Venezuelan herbaria, and from publications about bryophytes collected in Venezuela. It is concluded that Venezuela, despite having been little explored, has a great bryophyte diversity. Many species are unknown and could disappear before collection and scientific analysis.