Global Software Development (GSD) is currently a strong industry trend. This means that if computer science engineers are to be trained to deal with this model, it is very important to include the topic in software engineering courses, attempting to ensure that students learn about GSD and become familiar with its advantages and challenges. However, software engineering courses do not always consider including it in their curricula. It must also be recognized that it is difficult to find a suitable method to teach/develop the different skills needed for GSD. There is often a lot of content and not a great deal of time available to teach it. In this article, we propose the use of a serious game called GSD-Aware, with which students can “suffer” some of the typical challenges of GSD by interacting with avatars and by using several means of communication to solve a number of problems posed. The article focuses on the description of the game and on the empirical study conducted to analyze whether GSD-Aware helps students to be conscious of GSD challenges. It was discovered that after 50 minutes playing the game, the students were aware of the greater influence that the following factors can have: lack of coordination, lack of trust, cultural differences, lack of face-to-face and informal communication, time difference, and lack of team spirit. In their final analysis, students agreed that the serious game scenarios helped them to understand what GSD is and to grasp the importance of some GSD challenges.