A monoid M is called surjunctive if every injective cellular automata with finite alphabet over M is surjective. We show that all finite monoids, all finitely generated commutative monoids, all cancellative commutative monoids, all residually finite monoids, all finitely generated linear monoids, and all cancellative one-sided amenable monoids are surjunctive. We also prove that every limit of marked surjunctive monoids is itself surjunctive. On the other hand, we show that the bicyclic monoid and, more generally, all monoids containing a submonoid isomorphic to the bicyclic monoid are non-surjunctive.