The theory of twistors on foliated manifolds is developed. We construct the twistor space of the normal bundle of a foliation. It is demonstrated that the classical constructions of the twistor theory lead to foliated objects and permit to formulate and prove foliated versions of some well-known results on holomorphic mappings. Since any orbifold can be understood as the leaf space of a suitably defined Riemannian foliation we obtain orbifold versions of the classical results as a simple consequence of the results on foliated mappings.