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Journal of Computational Biology
Article . 2015 . Peer-reviewed
License: CC BY
Data sources: Crossref
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PubMed Central
Article . 2015
Data sources: PubMed Central
DBLP
Article . 2015
Data sources: DBLP
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Consequences of Common Topological Rearrangements for Partition Trees in Phylogenomic Inference

Authors: Olga Chernomor; Bui Quang Minh; Arndt von Haeseler;
APC: 3,463.45 EUR

Consequences of Common Topological Rearrangements for Partition Trees in Phylogenomic Inference

Abstract

Abstract In phylogenomic analysis the collection of trees with identical score (maximum likelihood or parsimony score) may hamper tree search algorithms. Such collections are coined phylogenetic terraces. For sparse supermatrices with a lot of missing data, the number of terraces and the number of trees on the terraces can be very large. If terraces are not taken into account, a lot of computation time might be unnecessarily spent to evaluate many trees that in fact have identical score. To save computation time during the tree search, it is worthwhile to quickly identify such cases. The score of a species tree is the sum of scores for all the so-called induced partition trees. Therefore, if the topological rearrangement applied to a species tree does not change the induced partition trees, the score of these partition trees is unchanged. Here, we provide the conditions under which the three most widely used topological rearrangements (nearest neighbor interchange, subtree pruning and regrafting, and tree bisection and reconnection) change the topologies of induced partition trees. During the tree search, these conditions allow us to quickly identify whether we can save computation time on the evaluation of newly encountered trees. We also introduce the concept of partial terraces and demonstrate that they occur more frequently than the original “full” terrace. Hence, partial terrace is the more important factor of timesaving compared to full terrace. Therefore, taking into account the above conditions and the partial terrace concept will help to speed up the tree search in phylogenomic inference.

Country
Austria
Keywords

Nearest neighbor interchange, nearest neighbor interchange, 106005 Bioinformatik, RATES, MAXIMUM-LIKELIHOOD PHYLOGENIES, partial terraces, Subtree pruning and regrafting, Research Articles, Phylogeny, SEQUENCES, Phylogenetic terraces, phylogenetic terraces, subtree pruning and regrafting, tree bisection and reconnection, Decision Trees, Genomics, TIME, Tree bisection and reconnection, LIFE, Partial terraces, SUPERMATRIX APPROACH, TERRACES, 106005 Bioinformatics, Software

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
16
Top 1%
Top 1%
Top 10%
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