Ventilation is pivotal in terms of securing optimum indoor air quality. In addition, it also has a major impact on energy use in buildings. It is important, therefore, that the role and impact of ventilation is fully understood and that ventilation is employed efficiently. The purpose of this paper is to review these aspects with particular reference to recent research and developments. Key aspects are concerned with identifying the role of ventilation and reviewing this role in the context of the other measures that must be taken to secure a healthy indoor environment. References are particularly made to the development of standards and recent related research. Although good progress is being made, areas that still need to be addressed include maintaining good outdoor air quality and preventing contaminated outdoor air from entering buildings. The outcome of recent research must also be disseminated in practical ways to policy makers, building occupiers and practitioners. Good indoor climate can be achieved, not so much by introducing expensive concepts, but by developing a rationale approach to identifying needs and applying the necessary tools to deal with each need.