The originally monotypic familyGomphillaceaeW. Wats. exHaf. 1984 (Type=GomphillusNyl.) is here enlarged to accomodate nine additional genera:AulaxinaFee,CaleniaMull. Arg. emSant.,EchinoplacaFee em.Sant.,GyalectidiumMull. Arg.,GyalideopsisVězda,TrichariaFee em.Sant. (all previously considered as a group of related genera in the familyAsterothyriaceae), andActinoplacaMull. Arg., as well as two new genera described here,BullatinaVezda etPoelt andCaleniopsisVězda etPoelt. Particular attention is given to the diversity of the structure of the hyphophores which are specific to all the genera now included in the familyGomphillaceae and therefore assist in the accurate delimitation of these genera. A short description of each genus is appended, together with a list of species included. A key to the genera is presented and their interrelationships discussed.