
doi: 10.1007/11533719_7
In computational biology, gene order data is often modelled as signed permutations. A classical problem in genome comparison is to detect conserved segments in a permutation, that is, genes that are co-localised in several species, indicating that they remained grouped during evolution. A second largely studied problem related to gene order data is to compute a minimum scenario of reversals that transforms a signed permutation into another. Several studies began to mix the two problems, and it was observed that their results are not always compatible : often parsimonious scenarios of reversals break conserved segments. In a recent study, Bérard, Bergeron and Chauve stated as an open question whether it was possible to design a polynomial time algorithm to decide if there exists a minimum scenario of reversals that transforms a genome into another while keeping the clusters of co-localised genes together. In this paper, we give this polynomial algorithm, and thus generalise the theoretical result of the aforementioned paper.
[INFO.INFO-OH] Computer Science [cs]/Other [cs.OH], [SDV.OT] Life Sciences [q-bio]/Other [q-bio.OT], REVERSAL SORTING, GENOME REARRANGEMENTS, COMMON INTERVALS, CONSERVED SEGMENTS, COMPUTATIONAL BIOLOGY
[INFO.INFO-OH] Computer Science [cs]/Other [cs.OH], [SDV.OT] Life Sciences [q-bio]/Other [q-bio.OT], REVERSAL SORTING, GENOME REARRANGEMENTS, COMMON INTERVALS, CONSERVED SEGMENTS, COMPUTATIONAL BIOLOGY
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 6 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
