Hierarchical models for multicentre binary response studies
Copyright policy )Hierarchical models for multicentre binary response studies
AbstractA three‐stage hierarchical model is proposed for two treatment, binary response studies conducted in a number of centres. The approach adopted is Bayesian. Marginal densities for second stage parameters are shown to provide useful summaries both of comparative efficacy and of the heterogeneity of treatment effects across centres. Sensitivity studies of model assumptions are illustrated.
- University of Nottingham United Kingdom
Clinical Trials as Topic, Models, Statistical, Bayes Theorem, Therapeutics, Sensitivity and Specificity, Placebos, Logistic Models, Odds Ratio, Humans, Multicenter Studies as Topic, Monte Carlo Method, Probability
Clinical Trials as Topic, Models, Statistical, Bayes Theorem, Therapeutics, Sensitivity and Specificity, Placebos, Logistic Models, Odds Ratio, Humans, Multicenter Studies as Topic, Monte Carlo Method, Probability
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