AbstractThe January‐February 2024 issue of the Hastings Center Report includes two sets of pieces concerning brain health. One is a special report on ethical challenges that emerge at various points in the care of people facing dementia. The other set launches the journal's Neuroscience and Society series. An At Law essay provides a framework for challenging discriminatory practices related to the use of algorithms generated by electronic prescription drug monitoring programs in health care. The issue also contains policy recommendations for the use of companion digital humans to address social isolation and loneliness, guidance for the rollout of vaccine delivery technologies, and a call for ethical investigation of data infrastructure.