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Angewandte Chemie
Article . 2013 . Peer-reviewed
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Angewandte Chemie International Edition
Article . 2013 . Peer-reviewed
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HAL Evry
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Binary Genetic Cassettes for Selecting XNA‐Templated DNA Synthesis In Vivo

Authors: Pezo, Valérie; Liu, Feng Wu; Abramov, Mikhail; Froeyen, Mathy; Herdewijn, Piet; Marlière, Philippe;

Binary Genetic Cassettes for Selecting XNA‐Templated DNA Synthesis In Vivo

Abstract

Hereditary information, coded in two bases, can be conveyed to DNA in vivo in the form of cyclohexenyl nucleic acid (CeNA), arabinofuranosyl nucleic acid (AraNA), and hexitol nucleic acid (HNA) messages. It was thus demonstrated that a binary genetic cassette can be used for the title process.

sponsorship: GOA 10/013 IDO FWO Vlaanderen Genoscope (Genopole, Evry)(ATIGE, EA 4527, UPS 3509) FP7/2007-2013)/ERC Grant agreement n° ERC-2012- ADG_20120216/320683.XNA - xenobiotic nucleic acids.

Countries
France, Belgium, France
Keywords

Chemistry, Multidisciplinary, OLIGONUCLEOTIDES, Xenobiotics, Sugar Alcohols, Catalytic Domain, Cyclohexenes, Escherichia coli, uracil, NUCLEIC-ACIDS, NUCLEOSIDE, Hypoxanthine, Science & Technology, Base Sequence, Nucleotides, Escherichia coli Proteins, Organic Chemistry, RECOGNITION, DNA, Thymidylate Synthase, 34 Chemical sciences, Arabinose, [SDV] Life Sciences [q-bio], Chemistry, nucleic acids, hypoxanthine, Physical Sciences, REPLICATION, gene expression, thymidylate synthetase, 03 Chemical Sciences, BUILDING-BLOCKS

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
45
Top 10%
Top 10%
Top 10%
Green
bronze