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Topical and Systemic Antimicrobial Therapy for Venous Leg Ulcers

descriptionPublicationkeyboard_double_arrow_right Article 25 Jun 2014Publisher:American Medical Association (AMA)Journal:JAMA, volume 311, page 2,534 (issn: 0098-7484,

Authors: Susan O’Meara; Rachel Richardson; Benjamin A. Lipsky; Benjamin A. Lipsky; Benjamin A. Lipsky;

doi: 10.1001/jama.2014.4574

pmid: 25058087

Topical and Systemic Antimicrobial Therapy for Venous Leg Ulcers

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Abstract

Is treatment with topical or systemic antimicrobial agents associated with better venous leg ulcer healing compared with usual care (dressings and bandages without antimicrobials) or an alternative topical or systemic antimicrobial agent?Available evidence, from underpowered pooled data, neither supports nor refutes an association of systemic antibiotic therapy with improved venous leg ulcer healing. Among topical antimicrobials, cadexomer iodine may be associated with better healing compared with usual care.

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Keywords

Anti-Infective Agents, Local, Humans, Anti-Bacterial Agents, Varicose Ulcer

1 Research products, page 1 of 1

Antibiotics and antiseptics for venous leg ulcers
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