The role of cholesterol metabolism and various steroid abnormalities in autism spectrum disorders: A hypothesis paper
Copyright policy )The role of cholesterol metabolism and various steroid abnormalities in autism spectrum disorders: A hypothesis paper
Based on evidence from the relevant research literature, we present a hypothesis that there may be a link between cholesterol, vitamin D, and steroid hormones which subsequently impacts on the development of at least some of the “autisms” [Coleman & Gillberg]. Our hypothesis, driven by the peer reviewed literature, posits that there may be links between cholesterol metabolism, which we will refer to as “steroid metabolism” and findings of steroid abnormalities of various kinds (cortisol, testosterone, estrogens, progesterone, vitamin D) in autism spectrum disorder (ASD). Further research investigating these potential links is warranted to further our understanding of the biological mechanisms underlying ASD.Autism Res2017. © 2017 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research.Autism Res2017, 10: 1022–1044. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.
- French National Centre for Scientific Research France
- RMIT University Australia
- University of Glasgow United Kingdom
- Panthéon-Assas University France
- Queen Mary University of London
steroid hormones, Hydrocortisone, Autism Spectrum Disorder, [SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, 610, autism, vitamin D, Hydrocortisone/metabolism, [SDV.GEN] Life Sciences [q-bio]/Genetics, R Medicine (General), cortisol, Autism Spectrum Disorder/metabolism, Cholesterol/metabolism, Humans, Testosterone, Vitamin D, Literature Review, Progesterone, cholesterol, Estrogens, [SCCO] Cognitive science, Hormones/metabolism, Estrogens/metabolism, R1, Testosterone/metabolism, Hormones, Vitamin D/metabolism, [SDV] Life Sciences [q-bio], Cholesterol, testosterone, Progesterone/metabolism, estrogens
steroid hormones, Hydrocortisone, Autism Spectrum Disorder, [SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, 610, autism, vitamin D, Hydrocortisone/metabolism, [SDV.GEN] Life Sciences [q-bio]/Genetics, R Medicine (General), cortisol, Autism Spectrum Disorder/metabolism, Cholesterol/metabolism, Humans, Testosterone, Vitamin D, Literature Review, Progesterone, cholesterol, Estrogens, [SCCO] Cognitive science, Hormones/metabolism, Estrogens/metabolism, R1, Testosterone/metabolism, Hormones, Vitamin D/metabolism, [SDV] Life Sciences [q-bio], Cholesterol, testosterone, Progesterone/metabolism, estrogens
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).60 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!