Two formulations of the stochastic model predictive control (SMPC) problem for the control of large-scale drinking-water networks are presented in this chapter. The first approach, named chance-constrained MPC, makes use of the assumption that the uncertain future water demands follow some known continuous probability distribution while at the same time, certain risk (probability) for the state constraints to be violated is allocated. The second approach, named tree-based MPC, does not require any assumptions on the probability distribution of the demand estimates, but brings about a complexity that is harder to handle by conventional computational tools and calls for more elaborate algorithms and the possible utilization of sophisticated devices. Peer Reviewed