Spray-drying process preserves the protective capacity of a breast milk-derived Bifidobacterium lactis strain on acute and chronic colitis in mice
Copyright policy )Spray-drying process preserves the protective capacity of a breast milk-derived Bifidobacterium lactis strain on acute and chronic colitis in mice
AbstractGut microbiota dysbiosis plays a central role in the development and perpetuation of chronic inflammation in inflammatory bowel disease (IBD) and therefore is key target for interventions with high quality and functional probiotics. The local production of stable probiotic formulations at limited cost is considered an advantage as it reduces transportation cost and time, thereby increasing the effective period at the consumer side. In the present study, we compared the anti-inflammatory capacities of theBifidobacterium animalissubsp.lactis (B. lactis) INL1, a probiotic strain isolated in Argentina from human breast milk, with the commercial strainB. animalissubsp.lactisBB12. The impact of spray-drying, a low-cost alternative of bacterial dehydration, on the functionality of both bifidobacteria was also investigated. We showed for both bacteria that the spray-drying process did not impact on bacterial survival nor on their protective capacities against acute and chronic colitis in mice, opening future perspectives for the use of strain INL1 in populations with IBD.
- Délégation Nord-Ouest France
- University of Lille France
- Vrije Universiteit Brussel Belgium
- Centre national de la recherche scientifique Morocco
- National Scientific and Technical Research Council Argentina
Colitis/prevention & control, BIFIDOBACTERIA, Probiotic, Inflammatory bowel disease, Agricultural and Biological Sciences, Food science, Mice, https://purl.org/becyt/ford/1.6, Desiccation/methods, BREAST-MILK, Disease, Probiotics/administration & dosage, Secado por Pulverización, Internal medicine, Probiotics and Prebiotics, Gastroenterology, Ratón, Life Sciences, Spray Drying, Diversity and Function of Gut Microbiome, Colitis, Bifidobacterium animalis/isolation & purification, Technology, Pharmaceutical/methods, Medicine, COLITIS, mice, Immunology, Argentina, Enfermedades Intestinales, Microbiology, Article, Bifidobacterium lactis, Bifidobacterium animalis, Biochemistry, Genetics and Molecular Biology, Health Sciences, Genetics, Animals, Humans, Technology, Pharmaceutical, Desiccation, https://purl.org/becyt/ford/1, Molecular Biology, Biology, Inflammation, Gut flora, SPRAY-DRYING, Bacteriological Techniques, Microbial Viability, Milk, Human, Bacteria, Probiotics, FOS: Clinical medicine, Strain (injury), Milk, Human/microbiology, Functional Bowel Disorders and Gastrointestinal Health, Intestinal Diseases, Disease Models, Animal, Lactobacillus, FOS: Biological sciences, Bacteriological Techniques/methods, Fermentation, Dysbiosis, Bifidobacterium, Food Science
Colitis/prevention & control, BIFIDOBACTERIA, Probiotic, Inflammatory bowel disease, Agricultural and Biological Sciences, Food science, Mice, https://purl.org/becyt/ford/1.6, Desiccation/methods, BREAST-MILK, Disease, Probiotics/administration & dosage, Secado por Pulverización, Internal medicine, Probiotics and Prebiotics, Gastroenterology, Ratón, Life Sciences, Spray Drying, Diversity and Function of Gut Microbiome, Colitis, Bifidobacterium animalis/isolation & purification, Technology, Pharmaceutical/methods, Medicine, COLITIS, mice, Immunology, Argentina, Enfermedades Intestinales, Microbiology, Article, Bifidobacterium lactis, Bifidobacterium animalis, Biochemistry, Genetics and Molecular Biology, Health Sciences, Genetics, Animals, Humans, Technology, Pharmaceutical, Desiccation, https://purl.org/becyt/ford/1, Molecular Biology, Biology, Inflammation, Gut flora, SPRAY-DRYING, Bacteriological Techniques, Microbial Viability, Milk, Human, Bacteria, Probiotics, FOS: Clinical medicine, Strain (injury), Milk, Human/microbiology, Functional Bowel Disorders and Gastrointestinal Health, Intestinal Diseases, Disease Models, Animal, Lactobacillus, FOS: Biological sciences, Bacteriological Techniques/methods, Fermentation, Dysbiosis, Bifidobacterium, Food Science
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