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Structure, biosynthesis, and properties of kurstakins, nonribosomal lipopeptides from Bacillus spp.

Authors: Béchet, Max; Caradec, Thibault; Hussein, Walaa; Abderrahmani, Ahmed; Chollet, Marlène; Leclère, Valérie; Dubois, Thomas; +3 Authors

Structure, biosynthesis, and properties of kurstakins, nonribosomal lipopeptides from Bacillus spp.

Abstract

A new family of lipopeptides produced by Bacillus thuringiensis, the kurstakins, was discovered in 2000 and considered as a biomarker of this species. Kurstakins are lipoheptapeptides displaying antifungal activities against Stachybotrys charatum. Recently, the biosynthesis mechanism, the regulation of this biosynthesis and the potential new properties of kurstakins were described in the literature. In addition, kurstakins were also detected in other species belonging to Bacillus genus such as Bacillus cereus. This mini-review gathers all the information about these promising bioactive molecules.

Keywords

Antifungal Agents, Protein Conformation, MESH: Molecular Structure, Bacillus thuringiensis, Spreading, Microbiology, Kurstakins, Lipopeptides, MESH: Protein Conformation, MESH: Lipopeptides, Bacillus cereus, Microbiologie, Lipopeptides/biosynthesis/chemistry, nonribosomal synthesis, [INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM], MESH: Bacillus thuringiensis, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Antifungal Agents/chemistry, Molecular Structure, NRPS, MESH: Antifungal Agents, 540, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Life sciences, Nucleic Acid-Independent, Bacillus thuringiensis/metabolism, MESH: Bacillus cereus, Sciences du vivant, Peptide Biosynthesis, Nucleic Acid-Independent, MESH: Peptide Biosynthesis, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Bacillus cereus/metabolism

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
77
Top 10%
Top 10%
Top 10%
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