The objective of present studies deals with the Pharmacognostic and antioxidant studies of stems of Pyrostegia venusta Pres. Some distinct and different characters were observed with section of young thin stems. Physiochemical parameter ash value and LOD of powder of stem was 1.85% w/w and 6.53 % w/w respectively. The phytochemical investigation of extracts of stem of Pyrostegia venusta shows the presence of sterols, triterpenes, flavonoids and tannins. Total phenolic content of total methanolic extract was determined by using folin Ciocalteu method. The total phenolic content in methanolic extract was found to be 5.55 % w/w equivalent to Tannic acid. Petroleum ether, ethyl acetate soluble, ethyl acetate insoluble and methanol exract was found to be scavenger of DPPH radical. The present study on Pharmacognostical investigation of Pyrostegia venusta Pers. stems might be useful to supplement information in regard to its identification parameters assumed significantly in the way of acceptability of herbal drugs in present scenario lacking regulatory laws to control quality of herbal drugs. Key Words: Pyrostegia venusta Pers., Stems, Pharmacognostical, Physiochemical, Antioxidant, DPPH.