Genome editing technologies, particularly CRISPR/Cas, have revolutionized the field of fruit crop breeding and genetics. This paper provides a comprehensive overview of the current advances and prospects of CRISPR/Cas-mediated genome editing in fruit crops. We discuss the recent breakthroughs in fruit crop genome editing, including the development of precise editing techniques, the enhancement of fruit quality, and the improvement of disease resistance. We also explore the regulatory and ethical considerations surrounding the application of CRISPR/Cas in fruit crops. As we delve into the future, we highlight the potential for accelerating fruit crop breeding, expanding fruit varieties, and addressing global food security challenges. This review serves as a valuable resource for researchers, policymakers, and stakeholders interested in the transformative role of CRISPR/Cas in shaping the future of fruit crop agriculture.