This study aimed to determine the effectiveness of instructional video lessons on the performance of grade 6 learners in Science in the New Normal Education at Angatel Elementary School, Urbiztondo during the fourth quarter of the school year 2020-2021. The control and experimental groups marked an increase in their performance in the post-test, but the improvement was significantly greater in the Experimental Group having a mean difference of 4.03. The computed t-value of 3.837 is higher than the critical t-value of 1.993 at a .05 level of significance with 74 degrees of freedom. The null hypothesis that there is no significant difference in the level of performance of the two groups in the post-test is rejected. The pre-test and post-test of the control group indicate an improvement in their level of performance in Science 6. There is a significant difference in the performance based on the pre-test and post-test. The computed t-value is 14.126 which is higher than the critical t-value of 2.026 at a .05 level of significance with a degree of freedom of 37. There is a significant difference in the performance of the experimental group in the pre-test and post-test. The computed t-value of 31.220 is higher than the critical t-value of 2.026 at a .05 level of significance with a degree of freedom of 37. Thus, there was a significant improvement in the performance of the experimental group who were exposed to instructional video lessons. Elementary teachers should be encouraged to utilize instructional video lessons as an alternative teaching strategy to increase the level of performance of learners in Science.