This study determines the use of instructional methods and materials in teaching Fine and Applied Arts in colleges of education in South-West, Nigeria. The research design adopted for the study was descriptive research using survey methods. Therefore, all 141 Fine and Applied Arts lecturers in government owned were purposively selected for the study. The instrument for data collection was research designed questionnaire titled use of instructional methods and materials in teaching Fine and Applied Arts in colleges of education in South-West, Nigeria. The questionnaire was validated by three curriculum experts and three Fine and Applied Arts lecturers for face and content validity. Test re-test method was used for reliability study while the instrument was subjected to analysis using Cronbach alpha statistic. The value yielded 0.82, 0.77, 0.81, 0.71 and 0.67 respectively. Research questions 1, 3 and 5 were answered using mean rating while research questions 2 and 4 were answered using frequency count and percentage. The results indicated that project method, lecture method and discovery method were mostly used by the lecturers. Lecturer integrated Fine and Applied Arts students into the practical activities and used the equipment and materials regularly. The lecturers usually covered minimum standards. The major problem encountered by Fine and Applied Arts lecturers was inadequate time for practical work. Based on the finding of this study, it was recommended among others that the Fine and Applied Arts lecturers should be encouraged to attend seminars, workshops and conferences to update themselves in their teaching skills.