World Health Organization (1978) proposes the assumption of three-tier classification system including impairment, functional limitations and disability. Impairment leads to functional limitations and functional limitations leads to disability. An attempt is being made to study the effect of instructional programme on academic performance of primary schools’ students with dyslexia in Amravati Division of Maharashtra. The aim of this paper was to compare the mean academic achievement scores of Pre and Post-tests. Experimental method was adopted and the data were collected by means of an academic achievement test based on language and elementary mathematics and attitude scale. The study reveals that there is significant difference between mean academic achievement scores of boys and girls in the scores of Pre and Post-tests in language.