{"references": ["1. Bristow A F : Recombinant DNA derived insulin analogues as potentially useful therapeutic agents. Trends in Biotechnology, 1993; 11:301\u2013305.", "2. Feber D : Gene therapy: Safer and virus-free? Science, 2001; 294:1638\u20131642.", "3. Findlay I, Taylor A, Quircke P, Frazier R, Urquhart A : DNA fingerprinting from single cells. Nature, 1997; 389:555\u2013556.", "4. Forslund K, Sonnhammer E L L : Predicting protein function from domain content. Bioinformatics, 2008; 24:1681\u20131687.", "5. Gardner R L : Stem cells: potency, plasticity and public perception. Journal of Anatomy, 2002; 200(3):277\u201382.", "6. Hammer R E, Pursel V G, Rexroad CE, Wall RJ, Bolt D J, Ebert K M, Palmiter R D, Brinster RL : Production of transgenic rabbits, sheep and pigs by microinjection. Nature, 1985; 315:680\u2013683.", "7. Hansen G, Wright M S : Recent advances in the transformation of plants. Trends in Plant Science, 1999; 4:226\u2013231.", "8. Hubbard R : Monoclonal antibodies: production, properties and application. In: Topics in Enzyme and Fermentation Biotechnology (Wiseman, A. ed.) 1983; pp. 163\u2013196. Ellis Harwood, Chichester", "9. Lemieux B A, Aharoni A, Schena M : Overview of DNA chip technology. Molecular Breeding, 1998; 4:277\u2013289.", "10. Lipinsky E S : Chemicals from biomass: petrochemical substitution options. Science, 1981; 212:1465\u20131471.", "11. MacDonald C : Animal cell technology. Trends in Biotechnology, 1996; 14:325\u2013326.", "12. Miller M : The promise of biotechnology. Journal of Environmental Health, 1991; 54:13\u201314.", "13. Mironov V, Boland T, Trusk T, Forgacs G, Markwald R R : Organ printing: computer-aided jet-based 3D tissue engineering. Trends in Biotechnology, 2003; 21:157\u2013161.", "14. Mudgett R E : Solid state ferementation. In: Manual of Induatrial Microbiology and Biotechnology (Demain, A. L., Solomon, N. A., eds.), 1996; pp. 66\u2013 83. American Society of Microbiology, Washington DC.", "15. Potrykus I : Gene transfer to plants: Assessment and perspectives. Physiologia Plantarium, 1990; 79:125\u2013 134.", "16. Schmidt K : Genetic engineering yields first pest- resistant seeds. Science, 1994; 265:739.", "17. Schwerin M, Brockmann G, Vanselow J, Seyfert H M : Perspective of molecular genome analysis in livestock improvement\u2013an overview. Animal Research and Development, 1995; 42:14\u201326", "18. Wilmut I, Schnieke A E, McWhir J, Kind A J, Campbell H S : Viable offspring derived from foetal and adult mammalian cells. Nature, 1997; 385:810\u2013813"]}

Biotechnology is any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use. It applies the knowledge of biology to enhance and improve the environment, health, and food supply. Using biotechnology, scientists work to develop environment-friendly alternatives to fossil fuels and plastics; new medicines, vaccines and disease diagnostic tools and higher yielding and more nutrient-rich crop plants (Miller, 1991). Biotechnology affects every part of our lives in the 21st Century.