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The decreasing interest of students in active learning and problem solving approach by working in groups is felt as a challenge by many teachers. Overdependence of today's medical undergraduates on readymade study material and social media is a matter of concern for the medical fraternity. At the same time it is an opportunity to develop innovative teaching learning methods suitable to present scenario. We planned to evaluate impact of innovative teaching methods on attendance and academic performance of MBBS students. It was a longitudinal type of descriptive study conducted among MBBS students. ‘Must know’ content for different topics and innovative methods of teaching were decided through faculty consensus. To improve active learning social media chat groups were utilized and students were encouraged to make group presentation, small write up on spotters and to undergo open book exam as a group assignment. Their attendance records and performances were evaluated at the end of study period of 21 months. There was a significant increase in mean percentage of theory marks among those attending 75% classes from first to fourth terminal (p<0.001). Although practical exams also ≥ observed the same trend but it was not significant (p: 0.89). Intervention in form of innovative techniques of teaching and learning contributed in improving the performances of the students. Introduction of innovative teaching learning methods is the need of the hour to improve interest and academic performances of undergraduate students.