Abstract— The influence of actinomycete strain Streptomyces albogriseolus-89 (isolated from soils of Khevi region, Stepantsminda, Georgia) on growth and development, as well as the content of metabolites (chlorophylls, carotenoids, anthocyanins, ascorbic acid, proline, soluble phenols, total proteins, soluble carbohydrates) and peroxidase activity in leaves of durum wheat (T. durum Desf.) has been studied. It was established that inoculation of wheat seeds with the strain has stimulated stem and ear growth, positively affected protein content (raised by 12%) and peroxidase activity (increased by 1.3 times) as well as enhanced the yield and resistance of plant to biotic and abiotic stresses.