The dataset supporting our publication 'Ice loss in the European Alps until 2050 using a fully assimilated, deep-learning-aided 3D ice-flow model' in Geophysical Research Letters. The .zip archive contains a set of NetCDF files detailing: Initial optimised glacier states (geology-optimized...) Simulation results (Prog20...) Initial states and results are given by cluster (see Figure 1 in the paper), as shown in all filenames (C1 through to C12). Prognostic simulation filenames additionally distinguish between runs between 1999 and 2019 (Prog2020) and between 2020 and 2050 (Prog2050). 'NV'/'NoVel' and 'NT'/'NoThk' refer to simulations using the partial optimisation (optimisation without including velocity/thickness observations) as detailed in the paper. 'AV' at the end of the filename denotes the integrated area/volume results file, as opposed to the 2D raster results file. A 'V' before the cluster designation shows that the simulation used the variable SMB as opposed to the fixed SMB (see the paper for details). 'ID' before the cluster designation shows that the simulation was using extrapolated SMB based on the trend in SMB since 2000, instead of assuming the continuation of the current SMB. 'ID' on its own denotes linear extrapolation and 'IDQ' denotes quadratic extrapolation. 'SMBF' in the filename shows that the simulation used the SMB-elevation feedback.