The concept of andragogy was proposed by Malcom Knowles and stated six basic principles: i) need to know, ii) experience, iii) self-concept, iv) readiness, v) problem orientation and vi) intrinsic motivation. etc. As per the cognitive development theory, the adults are enough matured and very well-developed abstract and logical thinking. As dealing with adult learners the teacher has to take into consideration the principles of andragogical practices in the context of globalization and NEP 2020. It’s an urgent need of an hour in the context of Indian education system, wherein NEP 2020 proposed research universities, teaching universities and college centre universities, the researchers made an attempt to proposed andragogical practices in terms of teaching learning methodologies like; team based learning, case studies, reflective disclosure, debates, cognitive apprenticeship, role play, portfolio-based learning, neuroplasticity etc.