A research study title A comparative study to assess the stress level of examination practice in semester and annual system among the students of School of Nursing Science and Research, Sharda University, Greater Noida U.P. The objectives of the study were to assess the stress level among students in Semester and annual system of examination, to compare the stress level among students of semester and annual system of examination, to find out the association between semester and annual System of examination with selected demographic variables. A Quantitative research approach was used and the research design adopted for the study was Comparative research design was adopted for this study. Samples were selected by using random sampling technique. The sample consists of 100 students, who are in age group of between 17-23 years from the School of Nursing Science and Research, Sharda University of Greater Noida. The date was collected by using 2 tools Demographic variables and Likert scale, the self prepared questionnaire was used to assess the stress level of examination practice in semester and annual system among the students. The shows that stress level mean score and SD in semester system was 33.5±3.7 and mean score and SD in annual system was 28.9±4.5 and the mean difference was 4.5 (2.9-6.2). Thus the p-value came out to be <0.0001**. Hence the semester system students had more stress than the annual system students. According the level of stress , majority (56%) of semester system had moderate level of stress and (44%) were having severe level of stress and annual system students (90%) had moderate level of stress and (10%) of students were having severe level of stress.